James Henry Quello (April 21, 1914 – January 24, 2010) was a broadcaster and government official who notably served as acting Chairman of the Federal Communications Commission (FCC) in 1993. Described as a "conservative Democrat", Quello was first appointed to the FCC by Republican president Richard Nixon. Quello's term as acting chairman ended when Reed Hundt was confirmed by the Senate, and he stepped down from the FCC entirely in 1998.

Quello was a World War II veteran during the European conflict in 1941–1945 and was a friend of President Gerald Ford. At the time of his death he was the chairman of James H. Quello and Mary B. Quello Center for Telecommunication Management and Law at Michigan State University which was named in honor of the former commissioner and his wife. Up until his death Quello was also working as a consultant in the Government Affairs law office of Wiley Rein.